Pub. Date : 1978 Jul-Aug
PMID : 727216
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Renin stimulation during clonidine therapy in "low renin" essential hypertension. | Clonidine | renin | Homo sapiens |
| 2 | Renin stimulation during clonidine therapy in "low renin" essential hypertension. | Clonidine | renin | Homo sapiens |
| 3 | Plasma renin activity (PRA) was measured during the administration of clonidine (0.1 mg twice daily) to 11 patients with essential hypertension. | Clonidine | renin | Homo sapiens |
| 4 | In contrast, in a small group of "normal renin" patients (n = 4), PRA did not change significantly but tended to decrease on clonidine therapy from 9.2 +/- 3.4 at control to 3.3 +/- 2.0 at one week, 3.4 +/- 0.6 at four weeks, and 4.7 +/- 1.7 ng Al/ml/hr at eight weeks. | Clonidine | renin | Homo sapiens |
| 5 | Previous studies have implicated alpha-adrenergic receptors as the site of clonidine actions on blood pressure and renin release. | Clonidine | renin | Homo sapiens |