Title : Studies on microsomal cytochrome P-450, monooxygenases and epoxide hydrolase in cultured keratinocytes and intact epidermis from BALB/C mice.

Pub. Date : 1982 Oct

PMID : 7120116






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In vitro treatment of the cells or in vivo application to the skin of animals with the polycyclic aromatic hydrocarbons benz(a)anthracene (BA) or benzo(a)pyrene resulted in significant induction of AHH and 7-ED activities. benz(a)anthracene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
2 In vitro treatment of the cells or in vivo application to the skin of animals with the polycyclic aromatic hydrocarbons benz(a)anthracene (BA) or benzo(a)pyrene resulted in significant induction of AHH and 7-ED activities. benz(a)anthracene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus
3 BA (4 x 10(-4) M) induced AHH and 7-ED at least 12- and 4-fold, respectively, in either the keratinocytes or intact epidermis, whereas epoxide hydrolase activity was not altered in either preparation. benz(a)anthracene cytochrome P450, family 1, subfamily a, polypeptide 1 Mus musculus