Pub. Date : 1982 Sep
PMID : 7108267
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 8-MOP administered orally to CD-1 mice daily for 6 days caused 2-3 fold increases in hepatic aryl hydrocarbon hydroxylase (AHH), ethylmorphine N-demethylase and cytochrome P-450. | Methoxsalen | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 2 | Chronic administration of 8-MOP to hairless mice caused significant enhancement of hepatic ethylmorphine N-demethylase and cytochrome P-450 but had no effect on AHH; whereas chronically administered TMP had no significant effect on any of these parameters. | Methoxsalen | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |