Title : Suppression of prolactin secretion by benzodiazepines in vivo.

Pub. Date : 1982

PMID : 6979001






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin. Diazepam prolactin Rattus norvegicus
2 The benzodiazepine diazepam blocked stress-induced prolactin release and, when given during the critical period of proestrus, the proestrus surge of prolactin. Diazepam prolactin Rattus norvegicus
3 Diazepam administration also blunted the release of prolactin induced by dopaminergic receptor blockade following haloperidol, or by serotonergic receptor activation produced by fluoxetine, a serotonergic reuptake inhibitor plus 5-hydroxytryptophan, a serotonin precursor. Diazepam prolactin Rattus norvegicus
4 Inhibition of prolactin release by benzodiazepine was dose related, and inhibition was still evident after repeated diazepam injection. Diazepam prolactin Rattus norvegicus
5 The potency of three benzodiazepine analogues to inhibit prolactin release correlated with their potency to displace radiolabeled diazepam binding from brain membrane fractions or to induce other biological responses (clonazepam greater than diazepam greater than chlordiazepoxide). Diazepam prolactin Rattus norvegicus
6 The potency of three benzodiazepine analogues to inhibit prolactin release correlated with their potency to displace radiolabeled diazepam binding from brain membrane fractions or to induce other biological responses (clonazepam greater than diazepam greater than chlordiazepoxide). Diazepam prolactin Rattus norvegicus