Title : Correlation between specific DNA-methylation products and mutation induction at the HGPRT locus in Chinese hamster ovary cells.

Pub. Date : 1983 Jun-Jul

PMID : 6865996






1 Functional Relationships(s)
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1 The relationship between O6-methylguanine and induced mutations in CHO cells is similar to that previously reported in CHO cells for O6-ethylguanine and mutations (Heflich et al., 1982) and indicates that alkylation-induced mutations at the HGPRT locus in CHO cells are primarily associated with O6-alkylguanine formation. cho hypoxanthine-guanine phosphoribosyltransferase Cricetulus griseus