Title : Substrate-specificities of acid and alkaline ceramidases in fibroblasts from patients with Farber disease and controls.

Pub. Date : 1982 Aug 1

PMID : 6814427






1 Functional Relationships(s)
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1 Deficiency of acid ceramidase activity in fibroblasts from patients with Farber disease and intermediate activities in obligate heterozygotes were demonstrated with all ceramides examined except for N-hexanoylsphingosine (C(6:0)/C(18:1)), whereas alkaline ceramidase activity was unaffected. N-caproylsphingosine N-acylsphingosine amidohydrolase 1 Homo sapiens