Title : Extra- and intracellular Ca2+ requirements for lysosomal enzyme secretion in human neutrophils.

Pub. Date : 1982 Jul

PMID : 6814207






2 Functional Relationships(s)
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1 The inhibition of FMLP- and C5a-induced lysosomal enzyme secretion by the intracellular Ca2+ antagonist, 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate (TMB-8) was additive to lowering extracellular [Ca2+f] from 10(-4) M to 10(-6) M or blocking plasma membrane Ca2+ flux with verapamil. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate formyl peptide receptor 1 Homo sapiens
2 The inhibition of FMLP- and C5a-induced lysosomal enzyme secretion by the intracellular Ca2+ antagonist, 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate (TMB-8) was additive to lowering extracellular [Ca2+f] from 10(-4) M to 10(-6) M or blocking plasma membrane Ca2+ flux with verapamil. 8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate formyl peptide receptor 1 Homo sapiens