Pub. Date : 1981
PMID : 6791210
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Chronic treatment with the MAO-A inhibitor clorgyline and the MAO-B inhibitor pargyline showed significant inhibition of the alternate MAO enzyme as well, although this crossover effect was greater for pargyline than clorgyline. | Clorgyline | monoamine oxidase B | Homo sapiens |
2 | Tyramine pressor sensitivity changes accompanying administration of the MAO inhibitors were highly correlated with decreases in plasma MHPG (r = 0.92), supporting our previous data indicating the rank order of clorgyline greater than pargyline greater than deprenyl for enhancement of tyramine pressor sensitivity and, thus, suggesting that tyramine potentiation is primarily a function of MAO-A rather than MAO-B inhibition. | Clorgyline | monoamine oxidase B | Homo sapiens |