Title : Tranylcypromine and 15-hydroperoxyarachidonate affect arachidonic acid release in addition to inhibition of prostacyclin synthesis in calf aortic endothelial cells.

Pub. Date : 1980 Oct 25

PMID : 6776101






2 Functional Relationships(s)
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1 In this paper, we examined the effect of two known inhibitors of prostacyclin synthetase, tranylcypromine and 15-hydroperoxyarachidonate, on bradykinin-stimulated prostacyclin synthesis and arachidonic acid release from cellular phospholipids in endothelial cells derived from calf aorta. Epoprostenol kininogen 1 Bos taurus
2 These two inhibitors inhibit prostacyclin synthesis stimulated by bradykinin, arachidonic acid, and ionophore A23187. Epoprostenol kininogen 1 Bos taurus