Title : Inhibition of murine embryonic development by alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase.

Pub. Date : 1980 Aug 8

PMID : 6773783






2 Functional Relationships(s)
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1 Administration of the irreversible inhibitor of ODC, alpha-difluoromethylornithine, DFMO, 2% inthe drinking water during days 5-8 of gestation, abolished the inareases in uterine ODC activity, putrescine and spermidine concentrations and enhanced the activity of SAMDC. Eflornithine S-adenosylmethionine decarboxylase 1 Mus musculus
2 Administration of the irreversible inhibitor of ODC, alpha-difluoromethylornithine, DFMO, 2% inthe drinking water during days 5-8 of gestation, abolished the inareases in uterine ODC activity, putrescine and spermidine concentrations and enhanced the activity of SAMDC. Eflornithine S-adenosylmethionine decarboxylase 1 Mus musculus