Title : Role of histone tyrosines in nucleosome formation and histone-histone interaction.

Pub. Date : 1984 Jan 10

PMID : 6706950






5 Functional Relationships(s)
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1 We show that tyrosines 37, 40, and 42 of H2B are protected from iodination in intact core particles, as expected since these tyrosines lie within the H2B-H2A binding site. Tyrosine H2B clustered histone 21 Homo sapiens
2 We show that tyrosines 37, 40, and 42 of H2B are protected from iodination in intact core particles, as expected since these tyrosines lie within the H2B-H2A binding site. Tyrosine H2B clustered histone 21 Homo sapiens
3 We show that tyrosines 37, 40, and 42 of H2B are protected from iodination in intact core particles, as expected since these tyrosines lie within the H2B-H2A binding site. Tyrosine H2B clustered histone 21 Homo sapiens
4 Yet iodination of these tyrosines in denatured H2B does not interfere with nucleosome assembly. Tyrosine H2B clustered histone 21 Homo sapiens
5 In contrast, iodination of tyrosines 83 and 121 of H2B, as well as iodination of the tyrosines of H2A, increases the stability of the histone octamer core. Tyrosine H2B clustered histone 21 Homo sapiens