Title : Altered plasma protein-binding of prednisolone in patients with the nephrotic syndrome.

Pub. Date : 1984 Mar

PMID : 6702820






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Prednisolone binds in plasma to both albumin and transcortin. Prednisolone serpin family A member 6 Homo sapiens
2 Compared to normal volunteers, nephrotic patients had significantly higher mean (+/- SD) association constants for the albumin-prednisolone complex (4.20 +/- 2.10 X 10(3) M-1 v 2.26 +/- 0.46 X 10(3) M-1, P less than 0.005) and tended to have higher association constants for the transcortin-prednisolone complex. Prednisolone serpin family A member 6 Homo sapiens
3 The difference was attributable to lower albumin-bound and/or transcortin-bound, but not unbound, concentrations of prednisolone in plasma. Prednisolone serpin family A member 6 Homo sapiens