Pub. Date : 1983 Jul
PMID : 6655809
6 Functional Relationships(s)Download |
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Sentence | Compound Name | Protein Name | Organism |
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1 | [Experimental study of an ampicillin suppository (KS-R1) in adults and children]. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens | ||
2 | The peak time (Tmax) of occurrence after rectal dose of KS-R1 was earlier than that after oral dose of ABPC, and was equal to that after intramuscular dose of ABPC. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens | ||
3 | Urinary recovery of ABPC during 6 hours after rectal dose of KS-R1 was 24.0%, compared with 34.0% for the oral dose, 59.6% for the intramuscular dose and 61.4% for the intravenous dose. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens | ||
4 | The relative bioavailability of KS-R1, calculated on the basis of urinary recovery after intravenous administration of ABPC, was about 40%. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens | ||
5 | Peak plasma level (Cmax) of ABPC after rectal administration of 125 mg and 250 mg of KS-R1 was reached in 15 minutes, indicating 4.8 and 7.1 mcg/ml, respectively. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens | ||
6 | Peak time (Tmax) of ABPC after the rectal doses of KS-R1 was about 2 hours earlier than that after oral doses of ABPC. | Ampicillin | kinase suppressor of ras 1 | Homo sapiens |