Title : [Experimental study of an ampicillin suppository (KS-R1) in adults and children].

Pub. Date : 1983 Jul

PMID : 6655809






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 [Experimental study of an ampicillin suppository (KS-R1) in adults and children]. Ampicillin kinase suppressor of ras 1 Homo sapiens
2 The peak time (Tmax) of occurrence after rectal dose of KS-R1 was earlier than that after oral dose of ABPC, and was equal to that after intramuscular dose of ABPC. Ampicillin kinase suppressor of ras 1 Homo sapiens
3 Urinary recovery of ABPC during 6 hours after rectal dose of KS-R1 was 24.0%, compared with 34.0% for the oral dose, 59.6% for the intramuscular dose and 61.4% for the intravenous dose. Ampicillin kinase suppressor of ras 1 Homo sapiens
4 The relative bioavailability of KS-R1, calculated on the basis of urinary recovery after intravenous administration of ABPC, was about 40%. Ampicillin kinase suppressor of ras 1 Homo sapiens
5 Peak plasma level (Cmax) of ABPC after rectal administration of 125 mg and 250 mg of KS-R1 was reached in 15 minutes, indicating 4.8 and 7.1 mcg/ml, respectively. Ampicillin kinase suppressor of ras 1 Homo sapiens
6 Peak time (Tmax) of ABPC after the rectal doses of KS-R1 was about 2 hours earlier than that after oral doses of ABPC. Ampicillin kinase suppressor of ras 1 Homo sapiens