Title : Specificity of submaxillary gland sialyltransferases.

Pub. Date : 1983 Nov 22

PMID : 6639963






3 Functional Relationships(s)
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1 This method, which utilizes high performance liquid chromatography, distinguishes addition of sialic acid to the N-acetylgalactosamine vs. galactose residues of the mucin disaccharide Gal beta(1 leads to 3)GalNac, and can be used to distinguish formation of the 3"- and 6"-isomers of sialyllactose. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Bos taurus
2 For the bovine, ovine, and porcine submaxillary extracts, more than 95% of the activity with asialo ovine submaxillary mucin is due to formation of NeuAc alpha(2 leads to 6)GalNAc. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Bos taurus
3 The relative preference of the N-acetylgalactosaminide alpha(2 leads to 6) sialyltransferase for a monosaccharide vs. a substituted GalNAc may play a role in regulation of chain length during mucin synthesis. N-acetylgalactosaminuronic acid mucin 1, cell surface associated Bos taurus