Title : Antithrombin in vertebrate species: conservation of the heparin-dependent anticoagulant mechanism.

Pub. Date : 1983 Dec

PMID : 6607710






1 Functional Relationships(s)
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1 The purified vertebrate inhibitors all show the following physical and functional homologies to human antithrombin: (i) heparin-enhanced inhibition of both bovine thrombin and human Factor Xa, (ii) molecular masses of approximately 60,000, and (iii) heparin-induced increases in ultraviolet fluorescence. Heparin coagulation factor II, thrombin Bos taurus