Title : Suppression of cross-link formation in chloroethylnitrosourea-treated DNA by an activity in extracts of human leukemic lymphoblasts.

Pub. Date : 1984 May

PMID : 6585269






1 Functional Relationships(s)
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1 These observations indicate that the number of cross-links induced by the chloroethylnitrosoureas and, hence, their cytotoxicity, should be inversely related to O6-methylguanine-DNA methyltransferase content of a cell. 1-(2-chloroethyl)-1-nitrosourea O-6-methylguanine-DNA methyltransferase Homo sapiens