Title : Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and phytohemagglutinin-stimulated human lymphocytes.

Pub. Date : 1984 Sep

PMID : 6504022






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Studies on the kinetic properties of the enzymes with thymidine and ATP as the substrates and dTTP as the inhibitor showed clear differences between TK 1 and TK 2, but a close similarity between TK 2 and TK 2N. Adenosine Triphosphate thymidine kinase 2 Homo sapiens
2 Studies on the kinetic properties of the enzymes with thymidine and ATP as the substrates and dTTP as the inhibitor showed clear differences between TK 1 and TK 2, but a close similarity between TK 2 and TK 2N. Adenosine Triphosphate thymidine kinase 2 Homo sapiens
3 With ATP as the variable substrate, all three enzymes showed positive cooperative kinetics, but TK 2 and TK 2N lost the cooperativity in the presence of dTTP. Adenosine Triphosphate thymidine kinase 2 Homo sapiens