Title : Blockade of hp-GRF-40-induced GH release in normal men by a cholinergic muscarinic antagonist.

Pub. Date : 1984 Nov

PMID : 6434584






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1 In five healthy young men, pretreatment with the cholinergic muscarinic antagonist pirenzepine (0.6 mg/kg iv) almost completely abolished the rise in plasma growth hormone (GH) elicited by an iv bolus injection of 1 microgram/kg human pancreatic GH-releasing factor 1-40 (hp-GRF-40). Pirenzepine growth hormone 1 Homo sapiens