Title : Interaction of endosulfan and dietary vitamin A on rat hepatic drug metabolising enzymes.

Pub. Date : 1983

PMID : 6424426






1 Functional Relationships(s)
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1 Administration of vitamin A (10,000 I.U./100 g body weight) daily for ten days reduced the activity of the above mentioned enzymes, when vitamin A and endosulfan were given together, vitamin A reduced the endosulfan induced increase of microsomal proteins and cytochrome P-450 levels, the activity of NADPH cytochrome C-reductase, aminopyrine N-demethylase and aniline-hydroxylase. Vitamin A cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus