Pub. Date : 1984
PMID : 6373505
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Aldehyde reductase (AR) activity was measured in the brain, liver and heart of 23- to 26-month-old and 3-month-old male Wistar rats, using 5 substrates (p-nitrobenzaldehyde, D-glucuronate, D-xylose, DL-glyceraldehyde and pyridine 3-aldehyde). | 4-nitrobenzaldehyde | aldo-keto reductase family 1, member B7 | Rattus norvegicus |
| 2 | A significant increase of AR activity was found in whole brain of old rats with p-nitrobenzaldehyde (11%) and D-glucuronate (24%). | 4-nitrobenzaldehyde | aldo-keto reductase family 1, member B7 | Rattus norvegicus |
| 3 | A significant increase of AR activity was found in cerebellum (26%), brainstem (19%), hypothalamus (13%), striatum (11%) and midbrain (6%) of old rats; up to now, the determination of the enzyme activity in the different brain regions has been carried out only with p-nitrobenzaldehyde. | 4-nitrobenzaldehyde | aldo-keto reductase family 1, member B7 | Rattus norvegicus |
| 4 | A significant increase of AR activity of old rats was also found in liver with D-glucuronate (10%), DL-glyceraldehyde (23%) and pyridine 3-aldehyde (30%), and in heart with p-nitrobenzaldehyde (42%) and DL-glyceraldehyde (20%). | 4-nitrobenzaldehyde | aldo-keto reductase family 1, member B7 | Rattus norvegicus |