Title : Immunoregulation by macrophages. III. Prostaglandin E suppresses lymphocyte activation but not macrophage effector function during Salmonella enteritidis infection.

Pub. Date : 1984

PMID : 6327542






3 Functional Relationships(s)
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1 A major effect of indomethacin in vivo and of PGE2 in vitro however, was on the production and expression of IL1 and IL2. Dinoprostone interleukin 1 complex Mus musculus
2 Secretion of IL1 by macrophages in vitro was greatly enhanced in indomethacin treated mice and was suppressed in vitro by PGE2. Dinoprostone interleukin 1 complex Mus musculus
3 Prostaglandin E2 also inhibited IL1 dependent T-lymphocyte differentiation. Dinoprostone interleukin 1 complex Mus musculus