Pub. Date : 1983 Jul 14
PMID : 6307387
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of pH and iron content of transferrin on its binding to reticulocyte receptors. | Iron | serotransferrin | Oryctolagus cuniculus |
| 2 | It is proposed that the high affinity of apotransferrin for its receptor at lower pH values and low affinity at pH 7.0 or above allow transferrin to remain bound to the receptor when it is within acidic intracellular vesicles, even after loss of its iron, but also allow ready release from the cell membrane when it is exteriorized by exocytosis after iron uptake. | Iron | serotransferrin | Oryctolagus cuniculus |
| 3 | It is proposed that the high affinity of apotransferrin for its receptor at lower pH values and low affinity at pH 7.0 or above allow transferrin to remain bound to the receptor when it is within acidic intracellular vesicles, even after loss of its iron, but also allow ready release from the cell membrane when it is exteriorized by exocytosis after iron uptake. | Iron | serotransferrin | Oryctolagus cuniculus |