Title : In vitro and in vivo interactions of delta 8-tetra-hydrocannabinol and its metabolites with hepatic microsomal drug metabolizing enzyme systems of mice.

Pub. Date : 1981 Aug

PMID : 6271944






1 Functional Relationships(s)
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1 significantly decreased activities of p-nitroanisole O-demethylase and aniline hydroxylase in hepatic microsomes, accompanying a decrease of cytochrome P-450 content in case of delta 8-THC. delta-8-tetrahydrocannabinol cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus