Title : Effect of meclastine, an H1-antihistamine, on plasma ACTH in adrenal insufficiency.

Pub. Date : 1981 May

PMID : 6261510






2 Functional Relationships(s)
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1 In order to evaluate the possible role of endogenous histamine in ACTH secretion we investigated the effect of the H1 antagonist meclastine on plasma ACTH in patients with ACTH hypersecretion. Histamine proopiomelanocortin Homo sapiens
2 These results suggest that histamine is involved in the control of ACTH secretion, possibly by stimulation of CRF release. Histamine proopiomelanocortin Homo sapiens