Pub. Date : 1984 Jun 28-Jul 4
PMID : 6204206
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Correlation between inositol phospholipid hydrolysis and substance P receptors in rat CNS. | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |
| 2 | Previous studies have shown that substance P stimulates the hydrolysis of inositol phospholipids in peripheral tissues and in the hypothalamus, probably through stimulation of a polyphosphoinositide-specific phospholipase C (refs 9-11). | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |
| 3 | We have therefore investigated the distribution of 3H-labelled substance P binding sites within various rat brain regions and correlated this with the rate of substance P-induced hydrolysis of inositol phospholipids in the same areas of the CNS. | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |
| 4 | We found that the rate of inositol phospholipid hydrolysis was proportional to the number of binding sites specific for 3H-substance P, suggesting that binding sites revealed by 3H-substance P autoradiography correspond to functional substance P receptors. | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |
| 5 | We found that the rate of inositol phospholipid hydrolysis was proportional to the number of binding sites specific for 3H-substance P, suggesting that binding sites revealed by 3H-substance P autoradiography correspond to functional substance P receptors. | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |
| 6 | We found that the rate of inositol phospholipid hydrolysis was proportional to the number of binding sites specific for 3H-substance P, suggesting that binding sites revealed by 3H-substance P autoradiography correspond to functional substance P receptors. | Phosphatidylinositols | tachykinin precursor 1 | Homo sapiens |