Title : Glycosaminoglycan synthesis in bleomycin-induced pulmonary fibrosis: biochemistry and autoradiography.

Pub. Date : 1983 Nov

PMID : 6195665






2 Functional Relationships(s)
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1 Separation of the various labeled glycosaminoglycans by chondroitinase digestion and chromatography revealed a transient rise from controls (P less than or equal to 0.05) in the proportion of labeled chondroitin 4-sulfate at 5 days, followed by an increase from controls (P less than or equal to 0.05) in proportionate labeling of dermatan sulfate at 15 and 45 days postbleomycin. Glycosaminoglycans galactosamine (N-acetyl)-6-sulfatase Homo sapiens
2 Grain formation was greatly reduced by pretreatment of the slide sections with hyaluronidase and chondroitinase, demonstrating the specificity of the label for glycosaminoglycans. Glycosaminoglycans galactosamine (N-acetyl)-6-sulfatase Homo sapiens