Pub. Date : 1983 Aug 30
PMID : 6194818
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rapid suppression of alpha 1-fetoprotein gene transcription by dexamethasone in developing rat liver. | Dexamethasone | alpha-fetoprotein | Rattus norvegicus |
| 2 | The nuclear concentration of AFP mRNA, monitored by dot-blot hybridization, decreases to undetectable levels within 48 h, whereas that of albumin mRNA increases slightly, which indicates the selectivity of DEX action. | Dexamethasone | alpha-fetoprotein | Rattus norvegicus |
| 3 | These results show that DEX suppresses AFP gene expression at the transcriptional level and suggest a direct negative action of DEX-receptor complexes on the AFP chromatin transcription unit. | Dexamethasone | alpha-fetoprotein | Rattus norvegicus |
| 4 | These results show that DEX suppresses AFP gene expression at the transcriptional level and suggest a direct negative action of DEX-receptor complexes on the AFP chromatin transcription unit. | Dexamethasone | alpha-fetoprotein | Rattus norvegicus |