Pub. Date : 1982
PMID : 6175832
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We studied, in seven patients with essential hypertension, the acute effects of 0.25 mg prazosin, given intravenously, on blood pressure and plasma renin activity, the degree of alpha-blockade induced by the drug being assessed by comparing the increments in blood pressure following a test dose of phenylephrine before and after prazosin administration. | Prazosin | renin | Homo sapiens |
| 2 | Prazosin infusion caused, within 20 min, a marked reduction of the pressor response to phenylephrine, a significant increment in plasma renin activity, and no change in blood pressure. | Prazosin | renin | Homo sapiens |
| 3 | The increments in renin in response to isoproterenol were significantly greater, both in absolute and percent values, after rather than before prazosin. | Prazosin | renin | Homo sapiens |