Pub. Date : 1982 Feb 15
PMID : 6174466
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Regulation of rat alpha-fetoprotein production by methionine during ethionine-hepatocarcinogenesis. | Methionine | alpha-fetoprotein | Rattus norvegicus |
| 2 | The levels of serum alpha-fetoprotein (AFP) in rats were determined during hepatocarcinogenesis with ethionine, and the effects of methionine administration on serum AFP elevation in these animals were studied with the aim of investigating regulatory mechanisms of AFP was observed 6 weeks following the start of feeding a diet containing 0.25% ethionine and again at the 22nd week of feeding, when a well-differentiated hepatoma had already developed. | Methionine | alpha-fetoprotein | Rattus norvegicus |
| 3 | The levels of serum alpha-fetoprotein (AFP) in rats were determined during hepatocarcinogenesis with ethionine, and the effects of methionine administration on serum AFP elevation in these animals were studied with the aim of investigating regulatory mechanisms of AFP was observed 6 weeks following the start of feeding a diet containing 0.25% ethionine and again at the 22nd week of feeding, when a well-differentiated hepatoma had already developed. | Methionine | alpha-fetoprotein | Rattus norvegicus |
| 4 | These biphasic elevations of serum AFP concentrations in rats fed a 0.25% ethionine-containing diet decreased abruptly an significantly following a change to the basal diet either supplemented with or without 0.7% methionine. | Methionine | alpha-fetoprotein | Rattus norvegicus |
| 5 | The possibility that regulation of AFP production in these rats may correlate with methionine metabolisms is discussed on the basis of the experimental data obtained. | Methionine | alpha-fetoprotein | Rattus norvegicus |