Title : Effect of manipulation of gamma-glutamyl transpeptidase levels on biliary excretion of aflatoxin B1 conjugates.

Pub. Date : 1984 Jul

PMID : 6145525






6 Functional Relationships(s)
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1 Effect of manipulation of gamma-glutamyl transpeptidase levels on biliary excretion of aflatoxin B1 conjugates. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus
2 The reactive intermediate of aflatoxin B1 (AFB1) forms a glutathione conjugate (AFB1-GSH) and this has been shown to be a substrate for gamma-glutamyl transpeptidase (GGT) in vitro. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus
3 The reactive intermediate of aflatoxin B1 (AFB1) forms a glutathione conjugate (AFB1-GSH) and this has been shown to be a substrate for gamma-glutamyl transpeptidase (GGT) in vitro. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus
4 The reactive intermediate of aflatoxin B1 (AFB1) forms a glutathione conjugate (AFB1-GSH) and this has been shown to be a substrate for gamma-glutamyl transpeptidase (GGT) in vitro. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus
5 The reactive intermediate of aflatoxin B1 (AFB1) forms a glutathione conjugate (AFB1-GSH) and this has been shown to be a substrate for gamma-glutamyl transpeptidase (GGT) in vitro. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus
6 The involvement of GGT in the biliary excretion of AFB1-Cys-Gly was demonstrated by in vivo inhibition of GGT by administering AT125 to a group of animals (n = 3) 15 min prior to the injection of AFB1. Aflatoxin B1 gamma-glutamyltransferase 1 Rattus norvegicus