Pub. Date : 1982 Nov-Dec
PMID : 6130905
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Induction of UDP-glucuronosyltransferase activities in Gunn, heterozygous, and Wistar rat livers by pregnenolone-16 alpha-carbonitrile. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 2 | The effect of pregnenolone-16 alpha-carbonitrile (PCN) on UDP-glucuronosyltransferase (UDP-GT) activity was comprehensively examined in Wistar (JJ), heterozygous (Jj) and Gunn (jj) rats with eleven different acceptors for glucuronic acid. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 3 | The effect of pregnenolone-16 alpha-carbonitrile (PCN) on UDP-glucuronosyltransferase (UDP-GT) activity was comprehensively examined in Wistar (JJ), heterozygous (Jj) and Gunn (jj) rats with eleven different acceptors for glucuronic acid. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 4 | The effect of pregnenolone-16 alpha-carbonitrile (PCN) on UDP-glucuronosyltransferase (UDP-GT) activity was comprehensively examined in Wistar (JJ), heterozygous (Jj) and Gunn (jj) rats with eleven different acceptors for glucuronic acid. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 5 | The effect of pregnenolone-16 alpha-carbonitrile (PCN) on UDP-glucuronosyltransferase (UDP-GT) activity was comprehensively examined in Wistar (JJ), heterozygous (Jj) and Gunn (jj) rats with eleven different acceptors for glucuronic acid. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 6 | Thus, 3-MC, PB, and PCN induce UDP-GT activities toward different groups of acceptors of glucuronic acid. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |
| 7 | The results support the hypothesis that PCN induces a form of UDP-GT that preferentially conjugates the group-3 acceptors, bilirubin and DIG. | Pregnenolone Carbonitrile | UDP glycosyltransferase 2 family, polypeptide B | Rattus norvegicus |