Pub. Date : 1980 May
PMID : 6103674
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Analysis of beta-adrenoceptors mediating renin release produced by isoproterenol in conscious dogs. | Isoproterenol | renin | Canis lupus familiaris |
| 2 | Types of beta-adrenoceptors mediating renin release induced by isoproterenol were investigated in conscious dogs. | Isoproterenol | renin | Canis lupus familiaris |
| 3 | The nonselective beta-adrenoceptor blocking drugs propranolol, D-32, and pindolol significantly inhibited increases in heart rate and plasma renin activity and a fall of blood pressure produced by intravenous infusion of isoproterenol (10 microgram . | Isoproterenol | renin | Canis lupus familiaris |
| 4 | The selective beta 1-adrenoceptor blocking drug atenolol, at the oral dose of 6 mg/kg, which selectively suppressed isoproterenol-induced tachycardia, significantly inhibited the renin release caused by isoproterenol. | Isoproterenol | renin | Canis lupus familiaris |
| 5 | By contrast, the renin release induced by isoproterenol was not modified by the selective beta 2-adrenoceptor blocking drug IPS-339 at an oral dose of 3 mg/kg, which fully and selectively antagonized the fall of blood pressure in response to isoproterenol. | Isoproterenol | renin | Canis lupus familiaris |
| 6 | There was good correlation between suppression of isoproterenol-induced renin release and that of isoproterenol-induced tachycardia after various beta-adrenoceptor blocking drugs. | Isoproterenol | renin | Canis lupus familiaris |