Title : Relationship between leukopenia and bone marrow myeloperoxidase in the rat treated with propylthiouracil.

Pub. Date : 1984 Oct

PMID : 6096612






5 Functional Relationships(s)
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1 Relationship between leukopenia and bone marrow myeloperoxidase in the rat treated with propylthiouracil. Propylthiouracil myeloperoxidase Rattus norvegicus
2 The relationship between the toxic effect of propylthiouracil (PTU) and myeloperoxidase activity of rat bone marrow was examined. Propylthiouracil myeloperoxidase Rattus norvegicus
3 The relationship between the toxic effect of propylthiouracil (PTU) and myeloperoxidase activity of rat bone marrow was examined. Propylthiouracil myeloperoxidase Rattus norvegicus
4 The administration of PTU for 1 or 2 weeks caused a decrease in leukocyte count with the concomitant inhibition of the activity of myeloperoxidase in the bone marrow. Propylthiouracil myeloperoxidase Rattus norvegicus
5 The results suggest that the mechanism of inhibition of myeloperoxidase activity by PTU given in vivo or incubated with the enzyme in vitro may be the same. Propylthiouracil myeloperoxidase Rattus norvegicus