Pub. Date : 1984 Jun
PMID : 6090311
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pre-incubation of PMNs in vitro with the cyclo-oxygenase (COx) inhibitor piroxicam (50 microM) before stimulation with the chemotactic peptide f-met-leu-phe (FMLP, 10(-7)M) inhibited all of these responses. | Piroxicam | formyl peptide receptor 1 | Homo sapiens |
| 2 | Binding of 3H-FMLP was inhibited by piroxicam. | Piroxicam | formyl peptide receptor 1 | Homo sapiens |
| 3 | Piroxicam inhibited FMLP-induced aggregation by 31% (5.2 cm2/min versus 3.6 cm2/min, P less than 0.004) and O2- generation by 35% (15.8 nmol cytochrome c reduced versus 10.2 nmol, P less than 0.002). | Piroxicam | formyl peptide receptor 1 | Homo sapiens |