Title : Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C.

Pub. Date : 1984 Aug 30

PMID : 6089799






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens
2 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens
3 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens
4 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens
5 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens
6 Ionomycin can elevate intraplatelet Ca2+ and activate phospholipase A without activating phospholipase C. Human platelets exposed to ionomycin, a Ca2+ ionophore, exhibit activation of both phospholipases A2 and C. Such platelets manifest a rise in cytoplasmic Ca2+ (monitored by quin 2), a loss in phosphoinositides, formation of lysophosphatidylinositol, thromboxane B2, phosphatidic acid, and phosphorylated 47 kilodalton protein, and secretion. Ionomycin carbonic anhydrase 2 Homo sapiens