Title : Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension.

Pub. Date : 1984 Jun

PMID : 6089027






3 Functional Relationships(s)
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1 Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension. Clonidine proopiomelanocortin Homo sapiens
2 Clonidine increased plasma beta-endorphin concentration of the reacting patients by 17.53 +/- 1.68 pM/1 and in the non-reacting ones by 5.91 +/- 0.88 pM/1. Clonidine proopiomelanocortin Homo sapiens
3 Significant linear correlation was found between the clonidine-induced increase in plasma beta-endorphin level and the naloxone-induced change in mean blood pressure [r = 0.9572, n:24, p less than 0.001]. Clonidine proopiomelanocortin Homo sapiens