Pub. Date : 1976 Apr 15
PMID : 58843
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prompt elevation of rat serum alpha-fetoprotein by acute liver injury following a single injection of ethionine. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 2 | The mechanism of increased alpha-fetoprotein (AFP) production following a single injection of ethionine was investigated by using rats aged 5 weeks at the time of killing. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 3 | The mechanism of increased alpha-fetoprotein (AFP) production following a single injection of ethionine was investigated by using rats aged 5 weeks at the time of killing. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 4 | Marked elevations of serum AFP concentrations occurred within 4 days in both male and female rats after administration of DL-ethionine or L-ethionine, although the increased levels of serum AFP and liver triglyceride in the adults were less marked in the male than in the female. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 5 | Frequent administrations of adenosine triphosphate after a single dose of ethionine prevented the increases in liver triglyceride and serum AFP levels. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 6 | The serum AFP from ethionine-treated rats was immunologically and electrophoretically indistinguishable from that of fetal, carbontetrachloride-treated or hepatoma-bearing rats. | Ethionine | alpha-fetoprotein | Rattus norvegicus |
| 7 | These observations suggest that the increased production of AFP in ethionine-treated rats is closely associated with hepatic injury and is not the consequence of liver cell regeneration. | Ethionine | alpha-fetoprotein | Rattus norvegicus |