Title : Effect of calmodulin antagonists on calcium and ethanol-induced sleeping time in mice.

Pub. Date : 1985 Oct

PMID : 4070338






5 Functional Relationships(s)
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1 Effect of calmodulin antagonists on calcium and ethanol-induced sleeping time in mice. Ethanol calmodulin 2 Mus musculus
2 This investigation was carried out to determine if calcium prolongation of ethanol-induced sleep is mediated by calmodulin and a calmodulin-dependent protein kinase. Ethanol calmodulin 2 Mus musculus
3 This investigation was carried out to determine if calcium prolongation of ethanol-induced sleep is mediated by calmodulin and a calmodulin-dependent protein kinase. Ethanol calmodulin 2 Mus musculus
4 The results would suggest a probable mechanism in which Ca++ prolongs ethanol-induced sleeping time by activating tyrosine hydroxylase and tryptophan hydroxylase through intracerebral calmodulin and calmodulin-dependent protein kinase, which subsequently raise the levels of 5-HT, DA and NE. Ethanol calmodulin 2 Mus musculus
5 The results would suggest a probable mechanism in which Ca++ prolongs ethanol-induced sleeping time by activating tyrosine hydroxylase and tryptophan hydroxylase through intracerebral calmodulin and calmodulin-dependent protein kinase, which subsequently raise the levels of 5-HT, DA and NE. Ethanol calmodulin 2 Mus musculus