Title : Unusual chemical properties of N-terminal histidine residues of glucagon and vasoactive intestinal peptide.

Pub. Date : 1985 Feb 12

PMID : 3994995






3 Functional Relationships(s)
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1 Unusual chemical properties of N-terminal histidine residues of glucagon and vasoactive intestinal peptide. Histidine vasoactive intestinal peptide Homo sapiens
2 Similarly, in glucagon and vasoactive intestinal peptide (VIP), apparent pKa values of 7.60 +/- 0.04 and 7.88 +/- 0.18, respectively, were obtained for the alpha-amino of their N-terminal histidine, and pKa values of 7.43 +/- 0.09 and 7.59 +/- 0.18 were obtained for the imidazole function. Histidine vasoactive intestinal peptide Homo sapiens
3 Similarly, in glucagon and vasoactive intestinal peptide (VIP), apparent pKa values of 7.60 +/- 0.04 and 7.88 +/- 0.18, respectively, were obtained for the alpha-amino of their N-terminal histidine, and pKa values of 7.43 +/- 0.09 and 7.59 +/- 0.18 were obtained for the imidazole function. Histidine vasoactive intestinal peptide Homo sapiens