Title : Methylprednisolone half-life during simultaneous barbiturate treatment and mechanical hyperventilation of neurosurgical patients.

Pub. Date : 1985 Feb

PMID : 3968557






2 Functional Relationships(s)
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1 The half-life (t 1/2) for MP during barbiturate and hyperventilation therapy was found to be reduced by a mean 55% (p less than 0.01) in relation to the t 1/2 of MP when administered alone. barbituric acid interleukin 1 receptor like 1 Homo sapiens
2 Studies on the day after termination of barbiturate intake indicated a tendency for an increase in the t 1/2 of MP, but it was not significantly different from the pretermination assessment (p greater than 0.05). barbituric acid interleukin 1 receptor like 1 Homo sapiens