Title : Interaction of 3,4,3',4'-tetrachlorobiphenyl metabolites formed by cytochrome P-450 in vitro with rat erythrocytes.

Pub. Date : 1985 Oct

PMID : 3935092






1 Functional Relationships(s)
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1 Incubation of 14C-labeled 3,4,3",4"-tetrachlorobiphenyl (TCB) with a reconstituted monooxygenase system containing cytochrome P-450 isolated from 3-methylcholanthrene (MC)-treated rats caused an increase in incorporation of radioactivity to added rat erythrocytes and resulted in covalent binding of reactive metabolites to hemoglobin. Carbon-14 cytochrome P450, family 2, subfamily g, polypeptide 1 Rattus norvegicus