Title : The stimulations of arachidonic acid metabolism by recombinant murine interleukin 1 and tumor promoters or 1-oleoyl-2-acetyl-glycerol are synergistic.

Pub. Date : 1985 Nov

PMID : 3930604






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Recombinant murine IL 1 stimulated arachidonic acid metabolism by rat liver cells (the C-9 cell line) and squirrel monkey smooth muscle cells, and in the presence of tumor promoters this stimulation was synergistic. Arachidonic Acid interleukin 1 complex Mus musculus
2 In the rat liver cells that had been prelabeled with [3H]arachidonic acid, the release of 6-keto-PGF1 alpha and arachidonic acid also was stimulated by the IL 1, and this release was synergistic in the presence of TPA. Arachidonic Acid interleukin 1 complex Mus musculus
3 OAG and TPA mimic the endogenous activator of protein kinase C, 1,2-diacylglycerol, and therefore IL 1 may amplify arachidonic acid metabolism during signal transmission processes. Arachidonic Acid interleukin 1 complex Mus musculus