Pub. Date : 1985 Sep 15
PMID : 3929789
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Immunochemical study on the contribution of hypolipidaemic-induced cytochrome P-452 to the metabolism of lauric acid and arachidonic acid. | lauric acid | cytochrome P450, family 4, subfamily a, polypeptide 1 | Rattus norvegicus |
| 2 | All of the hypolipidaemic drugs tested significantly induced the hydroxylation of lauric acid and, furthermore, this was accompanied by a concomitant 3-fold induction of a specific isoenzyme of cytochrome P-450 (termed cytochrome P-452) as determined by a single radial immunodiffusion technique. | lauric acid | cytochrome P450, family 4, subfamily a, polypeptide 1 | Rattus norvegicus |
| 3 | Cytochrome P-452 plays a significant role in the hydroxylation of lauric acid as evidenced by inhibition of hydroxylase activity in the presence of an anti-P-452 IgG fraction. | lauric acid | cytochrome P450, family 4, subfamily a, polypeptide 1 | Rattus norvegicus |