Title : Differences of neuronal sensitivity to amino acids and related compounds in the rat hippocampal slice.

Pub. Date : 1985 Sep 6

PMID : 3903554






2 Functional Relationships(s)
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1 The perfusion of slices of rat hippocampus with solutions containing N-methyl-DL-aspartic acid (NMA), kainic acid, ibotenic acid or quinolinic acid produced a reduction in the size of antidromically evoked population spikes in the CA1 pyramidal cells or dentate gyrus granule cells. Ibotenic Acid carbonic anhydrase 1 Rattus norvegicus
2 The relative potencies of these compounds on CA1 cells compared with granule cells were kainate 3.65, quinolinate 3.46, NMA 2.19 and ibotenate 1.50. Ibotenic Acid carbonic anhydrase 1 Rattus norvegicus