Pub. Date : 1986 Dec
PMID : 3795953
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Steroid products and their analogs induce oxygen-mediated damage of microsomal P-450 activities of cultured Leydig cells, whereas testosterone acetate protects P-450 from this damage [1]. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 2 | Several steroids which have varying effects on damage of P-450 in cultured Leydig cells inhibited substrate binding similarly (KdI = 3.8-12.8 microM). | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 3 | The results suggest that steroid binding to P-450 is necessary but not sufficient to increase oxygen free-radical damage of the testicular microsomal P-450. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |
| 4 | The results suggest that steroid binding to P-450 is necessary but not sufficient to increase oxygen free-radical damage of the testicular microsomal P-450. | Steroids | cytochrome P450 family 2 subfamily B member 6 | Homo sapiens |