Title : Phosphorothioate-modified oligodeoxyribonucleotides. III. NMR and UV spectroscopic studies of the Rp-Rp, Sp-Sp, and Rp-Sp duplexes, [d(GGSAATTCC)]2, derived from diastereomeric O-ethyl phosphorothioates.

Pub. Date : 1986 Nov 25

PMID : 3786144






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The spectroscopically detectable structural perturbations caused by replacement of phosphate oxygen with sulfur were mostly localized within the GsA moiety, and were greater for the Rp configuration wherein sulfur is oriented into the major groove of the B-helix. Phosphates GNAS complex locus Homo sapiens