Title : Effects of antiestrogens on the induction of vitellogenin and its mRNA in Xenopus laevis.

Pub. Date : 1986 Jun

PMID : 3736040






3 Functional Relationships(s)
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1 Pre-injection with tamoxifen or 4-hydroxytamoxifen suppressed the estrogen-dependent induction of vitellogenin in serum. Tamoxifen a1-a Xenopus laevis
2 4-Hydroxytamoxifen also inhibited the induction of intracellular vitellogenin and its mRNA by estrogen suggesting that this metabolite of tamoxifen is able to inhibit estrogen-induced transcription of the vitellogenin genes. Tamoxifen a1-a Xenopus laevis
3 4-Hydroxytamoxifen also inhibited the induction of intracellular vitellogenin and its mRNA by estrogen suggesting that this metabolite of tamoxifen is able to inhibit estrogen-induced transcription of the vitellogenin genes. Tamoxifen a1-a Xenopus laevis