Title : Comparison of the effects of 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine and 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on ferrochelatase activity and heme biosynthesis in chick embryo liver cells in culture.

Pub. Date : 1986 Apr

PMID : 3730932






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1 Comparison of the effects of 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine and 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine on ferrochelatase activity and heme biosynthesis in chick embryo liver cells in culture. 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine ferrochelatase Gallus gallus
2 3-Ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine (EDP) was shown to lack the ferrochelatase-lowering activity of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) in chick embryo liver cells in culture. 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine ferrochelatase Gallus gallus
3 3-Ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine (EDP) was shown to lack the ferrochelatase-lowering activity of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine (DDC) in chick embryo liver cells in culture. 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine ferrochelatase Gallus gallus
4 The inactivity of EDP as a ferrochelatase-lowering agent and its low porphyrinogenic potency was explained, at least in part, by its rapid transformation in aqueous solution to other nondihydropyridine products. 3-ethoxycarbonyl-1,4-dihydro-2,4-dimethylpyridine ferrochelatase Gallus gallus