Pub. Date : 1986 Jun
PMID : 3720920
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NADPH-dependent and -independent loss of cytochrome P-450 in control and phenobarbital-induced rat hepatic microsomes incubated with carbon tetrachloride. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 2 | Carbon tetrachloride-mediated loss of cytochrome P-450 has been compared in hepatic microsomes from untreated and phenobarbital-treated rats. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 3 | At concentrations of carbon tetrachloride greater than 2.5 mM, a direct effect (i.e., NADPH- independent) on cytochrome P-450 was observed. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |
| 4 | These data suggest that the susceptibility of specific forms of cytochrome P-450 to carbon tetrachloride can be duplicated in in vitro incubation. | Carbon Tetrachloride | cytochrome P450, family 2, subfamily g, polypeptide 1 | Rattus norvegicus |