Title : Acetylcholinesterase as polyelectrolyte in reaction with cationic substrates.

Pub. Date : 1987 Dec 10

PMID : 3691807






1 Functional Relationships(s)
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1 It is shown that the salt effect in acetylcholinesterase-catalyzed hydrolysis of 2-(N-methylmorpholinium)-ethylacetate can be quantitatively described by the equation log(k2/KS) = log(k2/KS) degrees--psi log[M+Z] following from Manning"s polyelectrolyte theory; the psi values for salts with univalent and bivalent cations at different pH values of the reaction medium were in accordance with the conclusions of the theory. Salts acetylcholinesterase (Cartwright blood group) Homo sapiens